Inhibitory Effect of Salmon and other Calcitonins on Calcium Release from Mouse Bone In Vitro

1 April 1971

journal article
Published by Canadian Science Publishing in Canadian Journal of Physiology and Pharmacology

Vol. 49 (4) , 263-267
https://doi.org/10.1139/y71-028

Abstract

Salmon calcitonin in a concentration of 0.8 ng/ml inhibited for 20 h cell-mediated release of ⁴⁵Ca from cultured mouse calvaria. Porcine calcitonin in a concentration of 2500 ng/ml was much less effective. The response (percent inhibition) to salmon calcitonin was proportional to the logarithm of the dose over the range 0.012–0.20 ng/ml, and may provide a very sensitive in vitro bioassay for salmon calcitonin.

Keywords

SALMON CALCITONIN
SUP
VITRO BIOASSAY
CULTURED MOUSE
MOUSE BONE
PERCENT INHIBITION
CELL MEDIATED
CALCIUM RELEASE
MOUSE CALVARIA

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