Cimetidine and Coumarin Therapy of Renal Cell Carcinoma
- 1 January 1991
- journal article
- clinical trial
- Published by S. Karger AG in Oncology
- Vol. 48 (2) , 102-106
- https://doi.org/10.1159/000226905
Abstract
Thirty-eight patients with metastatic renal-cell carcinoma (RCC) and 1 patient with a second primary RCC were treated with coumarin and cimetidine. Patients received 400 mg cimetidine p.o. daily and after 1 week 100 mg coumarin p.o. daily in addition until tumour progression. Two complete remissions (30 and 50+ months) and 3 partial remissions (14, 13, 8 months) could be achieved. Problems regarding possibly spontaneous regressions and comparable results of other treatment in RCC are discussed.Keywords
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