Intermolecular Interactions and Characterization of the Novel Factor Xa Exosite Involved in Macromolecular Recognition and Inhibition: Crystal Structure of Human Gla-domainless Factor Xa Complexed with the Anticoagulant Protein NAPc2 from the Hematophagous Nematode Ancylostoma caninum
- 14 November 2006
- journal article
- Published by Elsevier in Journal of Molecular Biology
- Vol. 366 (2) , 602-610
- https://doi.org/10.1016/j.jmb.2006.11.040
Abstract
No abstract availableKeywords
This publication has 34 references indexed in Scilit:
- Nematode Anticoagulant Protein c2 Reveals a Site on Factor Xa That Is Important for Macromolecular Substrate Binding to Human ProthrombinaseJournal of Biological Chemistry, 2002
- Unexpected binding mode of tick anticoagulant peptide complexed to bovine factor XaJournal of Molecular Biology, 1998
- X-ray Structure of Active Site-inhibited Clotting Factor XaPublished by Elsevier ,1996
- Anticoagulant repertoire of the hookworm Ancylostoma caninum.Proceedings of the National Academy of Sciences, 1996
- Ancylostoma caninum anticoagulant peptide: a hookworm-derived inhibitor of human coagulation factor Xa.Proceedings of the National Academy of Sciences, 1995
- Structure of Human Des(1-45) Factor Xa at 2·2 Å ResolutionJournal of Molecular Biology, 1993
- The coagulation cascade: initiation, maintenance, and regulationBiochemistry, 1991
- Surface-dependent reactions of the vitamin K-dependent enzyme complexesBlood, 1990
- Tick Anticoagulant Peptide (TAP) Is a Novel Inhibitor of Blood Coagulation Factor XaScience, 1990
- VITAMIN K-DEPENDENT CARBOXYLASEAnnual Review of Biochemistry, 1985