Hydrolyse des aminoacyl‐tARN par la phosphodiesterase du venin
- 1 August 1968
- journal article
- Published by Wiley in FEBS Letters
- Vol. 1 (3) , 156-158
- https://doi.org/10.1016/0014-5793(68)80046-8
Abstract
The influence of the esterification of the 3′(2′) hydroxyl group of tRNA on the hydrolysis by venom phosphodiesterase (Crotalus adamanteus) was studied. It was shown that this esterification does not change the rate of hydrolysis. At pH 7–8, no significant differences were observed either when the α amino group of the attached amino acid was free or blocked, or when the aminoacid contained a free carboxyl group or a second amino group (glutamic acid or lysine). Aminoacyl-AMP or oligopeptidyl-AMP can be prepared by this method.Keywords
This publication has 3 references indexed in Scilit:
- The behaviour of acetylphenylalanyl soluble ribonucleic acid in polyphenylalanine synthesisBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1966
- Action of Venom Phosphodiesterase on Deoxyribooligonucleotides Carrying a Monoesterified Phosphate on Carbon 3'Journal of Biological Chemistry, 1960
- Studies on PolynucleotidesPublished by Elsevier ,1959