SYNTHESIS OF RNA IN NEURONS OF THE HYPOGLOSSAL NERVE NUCLEUS, AFTER SECTION OF THE AXON, IN MICE
- 1 June 1969
- journal article
- Published by Wiley in Journal of Neurochemistry
- Vol. 16 (6) , 865-868
- https://doi.org/10.1111/j.1471-4159.1969.tb08974.x
Abstract
—: Synthesis of RNA in neurons of the hypoglossal nerve nucleus after axonal section was studied by means of [5‐3H]uridine administration and radioautographic counting techniques in mice. The results of the experiments were evaluated by counts of silver grains over the nucleoplasm and cytoplasm of the neurons. RNA synthesis was greater in neurons after axonal section, and this increase was evident from 12 hr after the operation. The greatest increases in the operated side were observed in the 1st, 2nd and 3rd days after operation. In the 7th and 14th days RNA synthesis was still greater in the hypoglossal nucleus of the sectioned nerve but the difference in the control nucleus was not so striking. In the 30th day synthesis of RNA in left and right hypoglossal nuclei was comparable.Keywords
This publication has 8 references indexed in Scilit:
- Axonal reaction and axoplasmic flow as studied by radioautographyNeurology, 1968
- ADENINE-H3 UPTAKE IN NERVOUS TISSUE, INCLUDING REGENERATING NERVE CELLS, AS COMPARED WITH OTHER TISSUES IN EUTHYROID, HYPO- AND HYPERTHYROID MALE RATSActa Neurologica Scandinavica, 1965
- DNA synthesis in injured neurons of adult miceJournal of Neurochemistry, 1965
- Comparative uptake of dl-lysine-H3 by normal and regenerative hypoglossal nerve cells in euthyroid, hypothyroid and hyperthyroid male ratsExperimental Neurology, 1964
- Changes in the Protein Content of the Spinal Motor Neurones of the Mouse after Severance of the AxonNature, 1962
- Incorporation of Orotic Acid-14C and Lysine-14C in Regenerating Single Nerve CellsNature, 1958
- A Histoautoradiographic Study of the Effect of Section of the Facial Nerve on the Uptake of Methionine-35S by the Cells of the Facial Nerve NucleusNature, 1958