Atrial natriuretic peptides: Receptors and second messengers
- 1 January 1989
- Vol. 10 (1) , 16-19
- https://doi.org/10.1002/bies.950100105
Abstract
Atrial natriuretic peptides appear to elicit their actions in some target tissues by binding to a novel cell‐surface transmembrane protein which possesses both peptide binding and guanylate cyclase activities. Ligand binding stimulates enzyme activity to produce increased intracellular concentrations of cyclic GMP which, in turn, mediates the cell's physiological response.Keywords
This publication has 13 references indexed in Scilit:
- Physiological Role of Silent Receptors of Atrial Natriuretic FactorScience, 1987
- Purification and characterization of two types of atrial natriuretic factor receptors from bovine adrenal cortex: Guanylate cyclase-linked and cyclase-free receptorsBiochemical and Biophysical Research Communications, 1987
- Cyclic GMP Cascade of VisionAnnual Review of Neuroscience, 1986
- Atrial natriuretic factor and cGMP inhibit amiloride-sensitive Na+ transport in the cultured renal epithelial cell line, LLC-PK1Biochemical and Biophysical Research Communications, 1986
- Biologically active atrial peptides.Journal of Clinical Investigation, 1985
- Effects of atriopeptin on particulate guanylate cyclase from rat adrenalBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1985
- Effect of native and synthetic atrial natriuretic factor on cyclic GMPBiochemical and Biophysical Research Communications, 1984
- Atrial natriuretic factor inhibits adenylate cyclase activityBiochemical and Biophysical Research Communications, 1984
- Purification and Sequence Analysis of Bioactive Atrial Peptides (Atriopeptins)Science, 1984
- A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in ratsLife Sciences, 1981