Abstract
The activity of rifamycin-SV was studied on 70 cases of pulmonary tuberculosis. The antibiotic was administered by intravenous drip infusion (either alone or associated with intramuscular injections), or by local injection, in sero-fibrinous pleurisy, pyothorax, abscesses and tubercular adenitis. By systemic administration, the drug was very well tolerated even after several mo. Its antibacterial activity in human tuberculosis is less than in animal experiments. The metabolism of rifamycin-SV partially explains these findings. By local applications, rifamycin-SV, is very active against tuberculous lesions.

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