Visceral leishmaniasis caused by Leishmania (Viannia) braziliensis in a patient infected with human immunodeficiency virus
Open Access
- 1 January 2002
- journal article
- case report
- Published by FapUNIFESP (SciELO) in Revista do Instituto de Medicina Tropical de São Paulo
- Vol. 44 (3) , 145-149
- https://doi.org/10.1590/s0036-46652002000300006
Abstract
The current article reports the case of a 19-month-old-girl, from the state of Minas Gerais, Brazil, with visceral leishmaniasis, by Leishmania (Viannia) braziliensis, and Human Immunodeficiency Virus (HIV) co-infection. The child's mother and father, aged 22 and 27 years old, respectively, were both HIV positive. The child was admitted to the General Pediatric Center, in Belo Horizonte, presenting high fever, fatigue, weight loss and enlargement of liver and spleen. Indirect immunofluorescent test revealed a titer of 1:320 for Leishmania. Such result was confirmed by the presence of amastigotes in bone marrow aspirate samples and culture of promastigote forms. Parasites were identified as being Leishmania (Viannia) braziliensis through PCR, using a L. braziliensis complex primer and a generic primer, followed by hibridization. Specific leishmaniasis therapy (GlucantimeÒ antimonial) was intravenously administered.Keywords
This publication has 22 references indexed in Scilit:
- Atypical Mucocutaneous Leishmaniasis Caused by Leishmania braziliensis in an Acquired Immunodeficiency Syndrome Patient: T-cell Responses and Remission of Lesions Associated with Antigen ImmunotherapyMemórias do Instituto Oswaldo Cruz, 1999
- Parasite Genotypically Related to a Monoxenous Trypanosomatid of Dog's Flea Causing Opportunistic Infection in an HIV Positive PatientMemórias do Instituto Oswaldo Cruz, 1998
- Leishmaniasis presenting as a dermatomyositis-like eruption in AIDSJournal of the American Academy of Dermatology, 1996
- Visceral Leishmaniasis Due to a Leishmania Variant That Shares Kinetoplast DNA Sequences with Leishmania braziliensis and Leishmania mexicana in a Patient Infected with Human Immunodeficiency Virus: Identification of the Leishmania Species with Use of the Polymerase Chain ReactionClinical Infectious Diseases, 1995
- Leishmania braziliensis causing visceral leishmaniasis in a patient with human immunodeficiency virus infection, identified with the aid of the polymerase chain reactionTransactions of the Royal Society of Tropical Medicine and Hygiene, 1993
- Mucocutaneous leishmaniasis and AIDS: case reportTransactions of the Royal Society of Tropical Medicine and Hygiene, 1993
- Disseminated American muco-cutaneous leishmaniasis caused by Leishmania brasiliensis brasiliensis in a patient with AIDS: a case reportMemórias do Instituto Oswaldo Cruz, 1992
- Diagnosis of New World leishmaniasis: Specific detection of species of the Leishmania braziliensis complex by amplification of kinetoplast DNAActa Tropica, 1992
- Disseminated American cutaneous leishmaniasis in a patient with AIDSMemórias do Instituto Oswaldo Cruz, 1987
- LEISHMANIA DONOVANI: AN OPPORTUNISTIC MICROBE ASSOCIATED WITH PROGRESSIVE DISEASE IN THREE IMMUNOCOMPROMISED PATIENTSThe Lancet, 1986