Task-dependent genetic influences on behavioral response of mice (Mus musculus) to acetaldehyde.
- 1 January 1978
- journal article
- research article
- Published by American Psychological Association (APA) in Journal of Comparative and Physiological Psychology
- Vol. 92 (4) , 749-758
- https://doi.org/10.1037/h0077506
Abstract
Acetaldehyde was employed as a pharmacological agent in behavioral tests designed to assess genetic influences upon response to the drug. When used as a poison in a conditioned taste aversion study, acetaldehyde was more effective at inducing aversions in DBA/2J mice than in C57BL/6J mice. C57 mice were more affected than were DBA mice by acetaldehyde effects on loss of righting reflex. Implications for postulated genetic control of ethanol preference and neurosensitivity are discussed.This publication has 4 references indexed in Scilit:
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- Acetaldehyde Oxidation by Hepatic Mitochondria: Decrease After Chronic Ethanol ConsumptionScience, 1975
- The effect of acetaldehyde on mitochondrial functionArchives of Biochemistry and Biophysics, 1974
- Brain Sensitivity to Alcohol in Inbred Mouse StrainsScience, 1966