Supernumerary small ring chromosome.
Open Access
- 1 December 1977
- journal article
- research article
- Published by BMJ in Journal of Medical Genetics
- Vol. 14 (6) , 447-451
- https://doi.org/10.1136/jmg.14.6.447
Abstract
A supernumerary small ring chromosome was found in 30% of cultured peripheral leucocytes and 50% of skin fibroblasts in a 6-year-old boy with mild mental retardation and midline cleft palate. The extra chromosome appeared to carry a densely staining region on Giemsa banding. The banding patterns of the remaining 46 chromosomes were normal. C banding indicated that the ring chromosome contained mainly centromeric constitutive heterochromatin. Chromosome analysis of both parents showed normal karyotypes by both conventional and banding techniques; thus the origin of the ring chromosome could not be determined.This publication has 17 references indexed in Scilit:
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