SCOP: a Structural Classification of Proteins database
Open Access
- 1 January 1997
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 25 (1) , 236-239
- https://doi.org/10.1093/nar/25.1.236
Abstract
The Structural Classification of Proteins (SCOP) database provides a detailed and comprehensive description of the relationships of all known proteins structures. The classification is on hierarchical levels: the first two levels, family and superfamily, describe near and far evolutionary relationships; the third, fold, describes geometrical relationships. The distinction between evolutionary relationships and those that arise from the physics and chemistry of proteins is a feature that is unique to this database, so far. SCOP also provides for each structure links to atomic co-ordinates, images of the structures, interactive viewers, sequence data, data on any conformational changes related to function and literature references. The database is freely accessible on the World Wide Web (WWW) with an entry point at URL http://scop.mrc-lmb.cam.ac.uk/scop/Keywords
This publication has 9 references indexed in Scilit:
- RASMOL: biomolecular graphics for allTrends in Biochemical Sciences, 1995
- Comparison of methods for searching protein sequence databasesProtein Science, 1995
- SCOP: a structural classification of proteins database for the investigation of sequences and structures.Journal of Molecular Biology, 1995
- A new generation of information retrieval tools for biologists: the example of the ExPASy WWW serverTrends in Biochemical Sciences, 1994
- Structural Mechanisms for Domain Movements in ProteinsBiochemistry, 1994
- Classification of protein foldsCurrent Opinion in Structural Biology, 1994
- New protein foldsCurrent Opinion in Structural Biology, 1994
- GenBankNucleic Acids Research, 1993
- The nucleic acid database. A comprehensive relational database of three-dimensional structures of nucleic acidsBiophysical Journal, 1992