Experiments on Thrombosis of the Superior Longitudinal Sinus

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Abstract
This was attempted in rabbit and dog by ligating the sinus with or without introducing thrombosis-promoting substances: thrombin, ethamolin (5% ethanol-amine oleate and 2% benzyl alc. in H2O), pieces of muscle, and pledgets of cotton-wool. Cautery of the sinus wall was also done. Thrombosis was rarely produced, and at most was partial and asymptomatic. It was noted that thrombin, effective in vitro, did not cause clotting in vivo; also, that sudden occlusion of the sinus produced no symptoms, indicating a highly efficient collateral circulation. The authors conclude that the idea that thrombosis may readily be induced in the superior longitudinal sinus evidently needs revision.