Effects of structure on binding to the 2,3,7,8-TCDD receptor protein and AHH induction--halogenated biphenyls.
Open Access
- 1 September 1985
- journal article
- review article
- Published by Environmental Health Perspectives in Environmental Health Perspectives
- Vol. 61, 21-33
- https://doi.org/10.1289/ehp.856121
Abstract
The quantitative structure-activity relationships (QSARs) for polychlorinated biphenyl (PCB) congeners have been determined by comparing the EC50 values for three in vitro test systems, namely, aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin O-deethylase ...Keywords
This publication has 75 references indexed in Scilit:
- Polybrominated biphenyls as aryl hydrocarbon hydroxylase inducers: structure-activity correlationsChemico-Biological Interactions, 1982
- Halogenated biphenyls as AHH inducers: Effects of different halogen substituentsLife Sciences, 1982
- Binding of polychlorinated biphenyls classified as either phenobarbitone-, 3-methylcholanthrene- or mixed-type inducers to cytosolic Ah receptorChemico-Biological Interactions, 1982
- Polychlorinated biphenyls as inducers of hepatic microsomal enzymes: Structure-activity rulesChemico-Biological Interactions, 1980
- Polychlorinated biphenyl isomers and congeners as inducers of both 3-methylcholanthrene- and phenobarbitone-type microsomal enzyme activityChemico-Biological Interactions, 1980
- Induction of different species of cytochrome P-450 by coplanar and noncoplanar isomers of hexachlorobiphenylLife Sciences, 1980
- Induction of both cytochromes P-450 and P-448 by 2,3′,4,4′,5-pentabromobiphenyl, a component of fireMasterBiochemical and Biophysical Research Communications, 1980
- 3,4,5,3′,4′-Pentachlorobiphenyl as a useful inducer for purification of rat liver microsomal cytochrome P448Biochemical and Biophysical Research Communications, 1979
- 2,4,5,3′,4′,5′-hexabromobiphenyl is both a 3-methylcholanthrene-and a phenobarbital-type inducer of microsomal drug metabolizing enzymesBiochemical and Biophysical Research Communications, 1978
- Separation of pure polychlorinated biphenyl isomers into two types of inducers on the basis of induction of cytochrome P-450 or P-448Chemico-Biological Interactions, 1977