Familial thyroxine-binding globulin deficiency: search for linkage with Xg blood groups
Open Access
- 1 September 1974
- journal article
- research article
- Published by BMJ in Journal of Medical Genetics
- Vol. 11 (3) , 271-274
- https://doi.org/10.1136/jmg.11.3.271
Abstract
Serum thyroxine-binding globulin (TBG), thyroxine, and thyrotrophin were estimated in members of a family with TBG deficiency. Xga red cell antigen status was also studied. TBG deficiency appeared to be inherited as an X-linked condition. Four male members of the family showed absent TBG and seven heterozygous women showed intermediate TBG levels. Five informative phase known members of the family showed no recombination between Xg and TBG.Keywords
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