Activated Basic Alumina Promotes a Mild, Clean and High-Yield Racemization-Free Synthesis of t-Butyl Esters from Chiral Acid Bromides and t-Butyl Alcohol
- 1 February 1994
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 23 (2) , 209-212
- https://doi.org/10.1246/cl.1994.209
Abstract
Esterification of a variety of acid bromides having even steric bulkiness with t-BuOH/activated basic alumina gave the corresponding t-butyl esters in good to excellent yields. In the case of chiral acid bromides, no racemization has been ascertained for the first time.Keywords
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