Five Golden Rings
- 10 March 2006
- journal article
- editorial
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 311 (5766) , 1382-1383
- https://doi.org/10.1126/science.1125298
Abstract
The antibiotic nisin bears five rings of different sizes in its structure. The enzyme that catalyzes the five distinct cyclization reactions is flexible, yet stringent, enough to form each ring in the correct order and conformation.Keywords
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