Huntington's Chorea in Northamptonshire

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Abstract
Northamptonshire is a county in which details of pedigrees containing patients suffering from Huntington's Chorea have been kept for the past 14 years. In some families these details cover a span of eight generations. Pleydell (1954) found the prevalence of this illness to be five cases per 100,000 in 1954 (eight choreic families in the county), but in 1955 he found four new affected patients in one family, making 6-5 cases per 100,000 in nine choreic families for the county. Reid (i960) found two new subjects in the tenth choreic family of the county.

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