Estriol Production Rates and Breast Cancer*
- 1 January 1978
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 46 (1) , 44-47
- https://doi.org/10.1210/jcem-46-1-44
Abstract
We have infused [6,7-3H]estrone or [6,73H]estradiol and [4-14C]estriol into seven women who had had breast cancer and into five normal postmenopausal women. We measured the endogenous concentrations and the metabolic clearance rates of estrone, estradiol, and estriol and calculated the bloodproduction rates for these steroids in each group. There were no significant differences between the respective measurements for each group. Our data does not support the argument that physiological amounts of estriol are protective against breast cancer development in women. {J Clin Endocrinol Metab46: 44, 1978)Keywords
This publication has 4 references indexed in Scilit:
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- In VivoStudies on the Metabolism of Estrogens by Muscle and Adipose Tissue of Normal MalesJournal of Clinical Endocrinology & Metabolism, 1976
- The Metabolic Clearance and Blood Production Rates of Estriol in Normal, Non-Pregnant WomenJournal of Clinical Endocrinology & Metabolism, 1976
- Metabolic clearance rates and interconversions of estrone and 17β-estradiol in normal males and femalesJournal of Clinical Investigation, 1968