Metastatic interstitial pneumonitis after autologous bone marrow transplantation: A consequence of reinjection of malignant cells?

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Abstract
Two cases of fatal interstitial pneumonitis developing after an autologous bone marrow transplantation are described. In both cases the autopsy revealed diffuse malignant pulmonary involvement. The first case involved a 4‐year‐old boy who had a Burkitt's lymphoma; the second case involved a 4‐year‐old girl with a neuroblastoma. The authors postulate that in these cases, the clinical picture may have been related to reinfusion of malignant cells.