A TA Repeat Polymorphism in the Estrogen Receptor Gene Is Associated with Osteoporotic Fractures but Polymorphisms in the First Exon and Intron Are Not
Open Access
- 1 November 2000
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Bone and Mineral Research
- Vol. 15 (11) , 2222-2230
- https://doi.org/10.1359/jbmr.2000.15.11.2222
Abstract
Estrogen and the estrogen receptor (ER) play a central role in bone metabolism as illustrated by the loss of bone mass after menopause and the osteopenia in individuals with defect aromatase or ER. W...Keywords
This publication has 45 references indexed in Scilit:
- Lack of Association Between Estrogen Receptor Genotypes and Bone Mineral Density, Fracture History, or Muscle Strength in Elderly WomenJournal of Bone and Mineral Research, 1999
- Change of bone mass in postmenopausal Caucasian women with and without hormone replacement therapy is associated with vitamin D receptor and estrogen receptor genotypesHuman Genetics, 1998
- Hormonal Predictors of Bone Loss in Elderly Women: A Prospective StudyJournal of Bone and Mineral Research, 1998
- Reduced bone density and osteoporosis associated with a polymorphic Sp1 binding site in the collagen type I α 1 geneNature Genetics, 1996
- Mammalian Mature Osteoclasts as Estrogen Target CellsBiochemical and Biophysical Research Communications, 1996
- Association of Estrogen Receptor Dinucleotide Repeat Polymorphism with OsteoporosisBiochemical and Biophysical Research Communications, 1995
- Analysis of a DNA Sequence Upstream of the Human Estrogen Receptor GeneaAnnals of the New York Academy of Sciences, 1993
- Dinucleotide repeat polymorphism in the human estrogen receptor (ESR) geneHuman Molecular Genetics, 1992
- Incidence of an estrogen receptor polymorphism in breast cancer patientsBreast Cancer Research and Treatment, 1991
- Evidence for a complex regulatory array in the first intron of the human adenosine deaminase gene.Genes & Development, 1989