A simple synthetic route to statine and statine analogues
- 1 January 1989
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 19,p. 1474-1475
- https://doi.org/10.1039/c39890001474
Abstract
The biologically important amino acid statine, (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid, as well as optically active statine analogues, are readily accessible in the ester form by simple reduction of the corresponding N,N-dibenzyl β-keto esters using NaBH4 followed by deprotection.Keywords
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