QUANTITATIVE-EVALUATION OF RHEUMATOID ARTHRITIC ACTIVITY WITH TC-99M HEDP

  • 1 January 1977
    • journal article
    • research article
    • Vol. 18  (10) , 973-976
Abstract
In an attempt to develop a quantitative method of evaluating rheumatoid arthritis activity, Tc-99m HEDP joint uptake values and joint-to-bone ratios were studied in 10 adult rheumatoid arthritis patients and 17 nonarthritic patients. A joint-to-bone activity ratio of 1.8 at the 4th hour after injection (RA Index) discriminated clinically active rheumatoid arthritic joints from control joints with 95% accuracy. Serial studies on 5 patients during drug trial demonstrated a positive correlation between RA Index and the clinical manifestations of rheumatoid arthritic activity. The RA Index may be a useful quantitative parameter of evaluation of rheumatoid arthritic activity following therapy.

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