Patients with low-grade dysplasia should be advised to undergo colectomy.

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Abstract
Once confirmed by an experienced gastrointestinal (GI) pathologist, all patients with ulcerative colitis (UC) found to have flat low-grade dysplasia (LGD) at a surveillance colonoscopy should undergo colectomy. (A discussion that includes raised or polypoid dysplasia, which may behave similarly to a sporadic adenoma (1,2), is beyond the scope of this article; all mention of LGD in this article refers to LGD in flat, colitis-involved mucosa.) This recommendation takes into account a number of features about the finding of LGD at surveillance described in the literature, as well as an appreciation for the limitations of dysplasia surveillance.