A Novel Epimerization System in Fungal Secondary Metabolism Involved in the Conversion of Isopenicillin N into Penicillin N inAcremonium chrysogenum

This publication has 44 references indexed in Scilit:

• Molecular Control of Expression of Penicillin Biosynthesis Genes in Fungi: Regulatory Proteins Interact with a Bidirectional Promoter Region
  Journal of Bacteriology, 2000
• .ALPHA.-Aminoadipyl-cysteinyl-valine Synthetases in .BETA.-Lactam Producing Organisms.
  The Journal of Antibiotics, 2000
• Gene organization and plasticity of the β-lactam genes in different filamentous fungi
  Antonie van Leeuwenhoek, 1999
• Biosynthesis and molecular genetics of cephamycins
  Antonie van Leeuwenhoek, 1999
• New aspects of genes and enzymes for β-lactam antibiotic biosynthesis
  Applied Microbiology and Biotechnology, 1998
• PENICILLIN AND CEPHALOSPORIN BIOSYNTHETIC GENES: Structure, Organization, Regulation, and Evolution
  Annual Review of Microbiology, 1992
• The cefG gene of Cephalosporium acremonium is linked to the cefEF gene and encodes a deacetylcephalosporin C acetyltransferase closely related to homoserine O-acetyltransferase
  Journal of Bacteriology, 1992
• Characterization of the Cephalosporium acremonium pcbAB gene encoding alpha-aminoadipyl-cysteinyl-valine synthetase, a large multidomain peptide synthetase: linkage to the pcbC gene as a cluster of early cephalosporin biosynthetic genes and evidence of multiple functional domains
  Journal of Bacteriology, 1991
• Analysis of the role of cysteine residues in isopenicillin N synthetase activity by site-directed mutagenesis.
  Proceedings of the National Academy of Sciences, 1987
• Isolation, sequence determination and expression in Escherichia coli of the isopenicillin N synthetase gene from Cephalosporium acremonium
  Nature, 1985