A study of foot-and-mouth disease virus strains by complement fixation: II. A comparison of tube and microplate tests for the differentiation of strains

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Abstract
SUMMARY: Several foot-and-mouth disease virus strains were examined by complement-fixation tests in microplates and in tubes. It was established that the two systems are comparable, although greater reproducibility is obtained with tube tests. While microplate tests are a satisfactory method for the differentiation of strains, tube tests provide a more precise method for the identification of small antigenic differences.