Evaluation of determination of theophylline concentrations by Seralyzer.
- 1 August 1986
- journal article
- research article
- Vol. 57 (2) , 147-9
Abstract
Determination of theophylline concentrations by Seralyzer in 28 paired serum and plasma samples disclosed almost identical results. Comparison of determinations by Seralyzer and enzyme-multiplied immunoassay in 31 paired serum samples disclosed significant underestimation by Seralyzer when recalibrated whenever results of analysis of a 15-micrograms/mL control exceeded limits of +/- 3 micrograms/mL. Determinations by Seralyzer did not differ significantly from enzyme-multiplied immunoassay with narrower limits of 15 +/- 2 micrograms/mL for Seralyzer calibration for 18 paired samples. Seralyzer results are sufficiently reliable for clinical use if the instrument is recalibrated whenever analysis of the 15-micrograms/mL control falls outside limits of +/- 2 micrograms/mL.This publication has 0 references indexed in Scilit: