Laparoscopic vs Open Adrenalectomy for the Treatment of Primary Hyperaldosteronism
Open Access
- 1 June 1999
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Surgery
- Vol. 134 (6) , 628-632
- https://doi.org/10.1001/archsurg.134.6.628
Abstract
PRIMARY hyperaldosteronism is an uncommon but surgically correctable disease that affects approximately 1 in every 200 hypertensive patients.1 First described by Jerome Conn in 1954, primary hyperaldosteronism is characterized by hypertension, hypokalemia, elevated plasma aldosterone, and low plasma renin activity. The most common underlying pathology for this syndrome is an aldosterone-producing adrenal adenoma. Primary hyperaldosteronism can also be caused by bilateral adrenal hyperplasia and other rarer diseases such as primary unilateral adrenal hyperplasia, glucocorticoid-responsive hyperaldosteronism, and adrenocortical carcinoma.Keywords
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