The Recognition and Significance of Acinus-Filling Processes of the Lungs1,2,3

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Abstract
The acinus is the anatomic unit responsible for the stippled and rosette appearances frequently seen on the abnormal chest roentgenogram. Roentgenographic acids in the detection of the acinar pattern are presented. This pattern serves to differentiate a relatively small number of diseases from the larger group of conditions which diffusely involves the lung. The diseases producing acinar consolidation have been subclassified according to pathogenesis. They have been briefly illustrated and discussed: diagnosis depends upon examination of the alveolar contents or biopsy. Application of the concept of acinar disease makes it possible to obtain essential information from the chest film. The acinar pattern is easily recognized in the earlier stage of the disease when interstitial involvement is minimal. It aids greatly in differential diagnosis and sets the basis for a productive investigation.

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