Surface antibodies of human myelogenous leukaemia leukocytes reactive with specific type-C viral reverse transcriptases
- 1 November 1978
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 276 (5685) , 230-236
- https://doi.org/10.1038/276230a0
Abstract
Purified immunoglobin (Ig) G from patients with chronic myelogenous leukemia specifically neutralized RT [reverse transcriptase] from feline leukemia virus while purified IgG from other types of leukemias and from normal blood cells were less reactive and in some cases preferentially reacted with RT from horizontally transmitted primate type-C viruses (simian sarcoma virus-gibbon ape leukemia virus group). This indicates the presence of a heterogeneous immune response to RT or to an RT-like molecule in humans.Keywords
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