Spasmolytic substances from Cimicifuga dahurica Maxim.
- 1 January 1976
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 24 (4) , 580-583
- https://doi.org/10.1248/cpb.24.580
Abstract
The search for spasmolytic principals of Cimicifuga dahurica MAXIM. (Ranunculaceae) with the guidance of the intestinal action resulted in the isolation of 2 active substances, visamminol and visnagin, in addition to isoferulic acid and norvisnagin. Norvisnagin was 1st isolated from a natural source. Pharmacological estimations using guinea pig jejunum revealed that the spasmolytic actions of visamminol and visnagin were 1/3 and 1/10 that of papaverine hydrochloride, respectively. Norvisnagin showed inactivity.This publication has 1 reference indexed in Scilit:
- Studies on the Constituents of Cimicifuga spp. IX. Structure of CimigolYAKUGAKU ZASSHI, 1975