Candidiasis: Detection by Gas-Liquid Chromatography of D-Arabinitol, a Fungal Metabolite, in Human Serum
- 2 November 1979
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 206 (4418) , 577-580
- https://doi.org/10.1126/science.493963
Abstract
D-Arabinitol was identified as a major metabolite of Candida species in human subjects. Gas-liquid chromatography was used to measure the concentration of D-arabinitol in serum. The study included subjects who were healthy and cancer patients who had proven invasive candidiasis or were colonized with Candida. D-Arabinitol concentrations greater than 1.0 microgram per milliliter were found in serum from patients with invasive infection. This technique may prove valuable in the diagnosis of invasive candidiasis.Keywords
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