Is Cisplatin-Induced Cell Death Always Produced by Apoptosis?
Top Cited Papers
- 1 April 2001
- journal article
- review article
- Published by Elsevier in Molecular Pharmacology
- Vol. 59 (4) , 657-663
- https://doi.org/10.1124/mol.59.4.657
Abstract
The platinum drugs represent a unique and important class of antitumor agents. The clinical development of the neutral, square planar, coordination complex cis -diamminedichloroplatinum(II) (cisplatin), marked in the 1970s a watershed in the treatment of cancer. Cisplatin is widely used for theKeywords
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