Alteration of Drug-Protein Binding in Renal Disease
- 1 January 1984
- journal article
- Published by Springer Nature in Clinical Pharmacokinetics
- Vol. 9 (Supplement) , 18-26
- https://doi.org/10.2165/00003088-198400091-00003
Abstract
The protein binding of acidic drugs but not basic drugs is decreased in serum from patients with poor renal function. This decreased binding is due to the retention of compounds that displace drugs...Keywords
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