Biodegradation of copolymers composed of optically active L‐lactide and (R)‐ or (S)‐1‐methyltrimethylene carbonate
- 2 October 2001
- journal article
- research article
- Published by Wiley in Journal of Polymer Science Part A: Polymer Chemistry
- Vol. 39 (22) , 3916-3927
- https://doi.org/10.1002/pola.10035
Abstract
Random copolymerizations of L‐lactide with (R)‐, (S)‐, or rac‐1‐methyltrimethylene carbonate with bis(pentamethylcyclopentadienyl) samarium‐methyl tetrahydrofuranate [(C5Me5)2SmMe(THF)] as a novel initiator provided high molecular weight polymers with low polydispersities. Biodegradation of the resulting polymers with tricine and {N‐[tris(hydroxymethyl)methyl]‐2‐aminoethane sulfonic acid (TES) buffers as well as activated sludge showed only a small weight loss, whereas the polymer with proteinase K revealed high biodegradability independent of the optical activity of 1‐methyltrimethylene carbonate. © 2001 John Wiley & Sons, Inc. J Polym Sci Part A: Polym Chem 39: 3916–3927, 2001Keywords
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