Families With Multiple Cases of Urinary System Tumors: Brief Communication

1 November 1977

journal article
research article
Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute

Vol. 59 (5) , 1419-1421
https://doi.org/10.1093/jnci/59.5.1419

Abstract

A study of three families living in villages with endemic nephropathy (EN) in Vratza district, Bulgaria, revealed 9 members with urinary system tumors (UST), 7 with UST and EN, and 7 with EN. Most cases were registered from 1962 to 1976. The predominant form was transitional cell neoplasms of the kidney pelvis and ureter in patients 40-60 years old. In about 40% of the patients more than one site in the urinary system was involved. One ovarian carcinoma was also registered In these families duro ing this period. Persons related by marriage and coming from nonendemic families and villages were also affected by both diseases. In other branches of the three families living in other households or villages, only one case of EN was found.

Keywords

This publication has 1 reference indexed in Scilit:

Geographic correlation between the occurrence of endemic nephropathy and urinary tract tumours in vratza district, Bulgaria
International Journal of Cancer, 1977