IDIOPATHIC HYPERLIPEMIA AND PRIMARY HYPERCHOLESTEREMIC XANTHOMATOSIS

Publisher Website
Google Scholar
Abstract
IN A PREVIOUS communication of this series1it had been reported that a single intravenous injection of 50 mg. of heparin consistently caused a slight decrease in serum cholesterol in primary hypercholesteremic xanthomatosis, and a slight decrease also in phospholipids, neutral fat, and turbidity in idiopathic hyperlipemia. Subsequently it was observed2that the prolonged administration of heparin caused a considerable decrease in turbidity and in all the lipid values in idiopathic hyperlipemia. In order to obtain information about the action of heparin on the serum lipoproteins, ultracentrifugal analyses of the lipoproteins were carried out before and after a single intravenous injection of 100 mg. of heparin in normal persons as well as in patients with primary hypercholesteremic xanthomatosis and idiopathic hyperlipemia. In addition, similar studies were carried out in several patients with idiopathic hyperlipemia before and during the prolonged administration of heparin. METHODS Blood was collected as

This publication has 0 references indexed in Scilit: