The Effect of 17-Hydroxycorticosterone and Related Adrenal Cortical Steroids on Sodium and Chloride Excretion

Abstract
The subcut. inj. of 5 and 8 mg. respectively of 17-hydroxycorticosterone was followed by a significant increase in the renal excretion of Na and chloride in a normal dog. Inj. of 25 mg. of ll-dehydro-17-hydroxycorticosterone increased Na and chloride excretion in both a normal dog and an adrenalectomized dog. Treatment with desoxy-corti-costerone or corticosterone was followed by a significant retention of Na and chloride.

This publication has 1 reference indexed in Scilit: