Decreased Erythrocyte Deformability in Cholestatic Jaundice
- 1 January 1971
- journal article
- Published by S. Karger AG in Acta Haematologica
- Vol. 46 (4) , 211-220
- https://doi.org/10.1159/000208577
Abstract
The anemia in experimental cholestatic jaundice has been studies in rabbits. A decreased erythrocyte deformability has been found in bile duct ligated animals and failed to be traceable in sham-operated ones. The deteriorated deformability of the red cells in a first step is caused by the action of surface active substances and secondly by other factors as a possibly deranged cell metabolism. Both factors will deteriorate the flexibility and thus the erythrocyte life-span.Keywords
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