Nature of lethality of t mutations in embryos
- 1 November 1977
- journal article
- review article
- Published by Springer Nature in Nature
- Vol. 270 (5633) , 137-140
- https://doi.org/10.1038/270137a0
Abstract
Mutations in the genes of the T complex in mice can lead to death at various stages ofembryogenesis. It has been suggested that the T genes specify cell surface antigens which are essential for normal organisation of certain cells within the embryo. But, there is now evidence that at least some of these T complex mutations are simply generalised cell lethals.Keywords
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