Intravitreal liposome-encapsulated drugs: A preliminary human report
- 1 January 1988
- journal article
- research article
- Published by Springer Nature in International Ophthalmology
- Vol. 12 (3) , 175-182
- https://doi.org/10.1007/bf00130002
Abstract
Intravitreal liposome-encapsulated antibiotics and antiviral drugs were used in patients with acute toxoplasmosis retinochoroiditis, presumed propionibacterium acne endophthalmitis after cataract surgery, and presumed cytomegalovirus retinitis associated with AIDS. A single intravitreal dose was effective in the treatment of all the conditions. Intravitreal liposomes may prove to be an advantageous drug delivery system for the treatment of chronic intraocular inflammatory disorders.This publication has 18 references indexed in Scilit:
- Evaluation of liposome-encapsulated clindamycin inStaphylococcus aureaus endophthalmitisInternational Ophthalmology, 1989
- Intravitreal Liposome-encapsulated Triofluorothymidine in a Rabbet ModelOphthalmology, 1987
- Use of Intravitreal Ganciclovir (Dihydroxy Propoxymethyl Guanine) for Cytomegalovirus Retinitis in a Patient With AIDSAmerican Journal of Ophthalmology, 1987
- INTRAVITREAL INJECTION OF LIPOSOME-ENCAPSULATED GANCICLOVIR IN A RABBIT MODELRetina, 1987
- Chronic Propionibacterium Endophthalmitis After Extracapsular Cataract Extraction and Intraocular Lens ImplantationAmerican Journal of Ophthalmology, 1986
- 5-fluorouracil: New Applications in Complicated Retinal Detachment for an Established AntimetaboliteOphthalmology, 1984
- Intravitreal administration of antibiotic in the treatment of bacterial endophthalmitis. III. ConsensusSurvey of Ophthalmology, 1982
- Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation.Proceedings of the National Academy of Sciences, 1978
- Intraocular Injection of GentamicinArchives of Ophthalmology (1950), 1974
- Bacterial EndophthalmitisArchives of Ophthalmology (1950), 1974