X-chromosome segregation, maternal age and aneuploidy in the XO mouse
- 1 February 1983
- journal article
- research article
- Published by Hindawi Limited in Genetics Research
- Vol. 41 (1) , 85-95
- https://doi.org/10.1017/s001667230002108x
Abstract
SUMMARY: Cytogenetic studies have ascertained that the segregation of the X-chromosome, during the first meiotic division of the oocyte in XO mice, occurs at random, contrary to the finding of some earlier authors. The ratio of nullo-X to X-bearing oocytes at ovulation does not change with maternal age. The usefulness of the XO mouse as a model for aneuploidy production in women (Lyon & Hawker, 1973) is discussed.This publication has 12 references indexed in Scilit:
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