The Behaviour of Various Platelet Function Tests During Long-Term Prostacyclin Infusion in Patients with Peripheral Vascular Disease

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Abstract
In 20 patients with peripheral vascular disease treated with prostacyclin (5 ng/kg/min) we observed a significant activation of platelet function as measured by platelet proteins, ADP- induced aggregation platelet sensitivity and platelet count. Only the platelet survival was significantly prolonged by the treatment.