Toxic Effects of Tacrine on Primary Hepatocytes and Liver Epithelial Cells in Culture
- 1 January 1998
- journal article
- Published by Springer Nature in Cell Biology and Toxicology
- Vol. 14 (5) , 361-373
- https://doi.org/10.1023/a:1007589808761
Abstract
Administration of tacrine (THA) for the treatment of Alzheimer's disease results in a reversible hepatotoxicity in 30–50% of patients, as indicated by an increase in transaminase levels. However, the...Keywords
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