Involvement of eosinophils in acute myeloid leukaemia with monosomy 7 demonstrated by fluorescence in situ hybridization
- 1 October 1994
- journal article
- case report
- Published by Wiley in British Journal of Haematology
- Vol. 88 (2) , 389-391
- https://doi.org/10.1111/j.1365-2141.1994.tb05035.x
Abstract
Summary. Monosomy 7 is the commonest monosomy in acute myeloid leukaemia (AML). A patient with AML and monosomy 7 was investigated by fluorescence in situ hybridization. Monosomy 7 could be demonstrated in the blasts and also in mature eosinophils, but apparently not in lymphocytes. Monosomy 7 may occur in a multipotential myeloid progenitor cell as part of the multi‐step leukaemogenic process.Keywords
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