Vaccination of Metastatic Melanoma Patients With Autologous Tumor-Derived Heat Shock Protein gp96-Peptide Complexes: Clinical and Immunologic Findings
Top Cited Papers
- 15 October 2002
- journal article
- clinical trial
- Published by American Society of Clinical Oncology (ASCO) in Journal of Clinical Oncology
- Vol. 20 (20) , 4169-4180
- https://doi.org/10.1200/jco.2002.09.134
Abstract
PURPOSE: To determine the immunogenicity and antitumor activity of a vaccine consisting of autologous, tumor-derived heat shock protein gp96-peptide complexes (HSPPC-96, Oncophage; Antigenics, Inc,...Keywords
This publication has 27 references indexed in Scilit:
- Interaction of Heat Shock Proteins with Peptides and Antigen Presenting Cells: Chaperoning of the Innate and Adaptive Immune ResponsesAnnual Review of Immunology, 2002
- HBV-specific peptide associated with heat-shock protein gp96The Lancet, 2001
- Quantitation of antigen-reactive T cells in peripheral blood by IFNγ-ELISPOT assay and chromium-release assay: a four-centre comparative trialJournal of Immunological Methods, 2000
- Immunological Gene Therapy withex VivoGene-Modified Tumor Cells: A Critique and a ReappraisalHuman Gene Therapy, 2000
- Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cellsNature Medicine, 1998
- Do human cancers express sharedprotectiveantigens? or The necessity of remembrance of things pastSeminars in Immunology, 1996
- Loss of HLA class I antigens by melanoma cells: molecular mechanisms, functional significance and clinial relevanceImmunology Today, 1995
- A Mechanism for the Specific Immunogenicity of Heat Shock Protein-Chaperoned PeptidesScience, 1995
- Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor.Proceedings of the National Academy of Sciences, 1994
- Model Predicting Survival in Stage I Melanoma Based on Tumor ProgressionJNCI Journal of the National Cancer Institute, 1989