Hyperthermia After Cardiac Arrest Is Associated With an Unfavorable Neurologic Outcome
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Open Access
- 10 September 2001
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 161 (16) , 2007-2012
- https://doi.org/10.1001/archinte.161.16.2007
Abstract
WITHIN recent years, strikingly consistent and persuasive evidence has shown that moderate hyperthermia, when present during or after a period of brain ischemia or trauma, markedly exacerbates the degree of resulting neural injury. In laboratory animals, the outcomes of focal and global cerebral ischemia are profoundly affected by alterations in body temperature.1,2 Experimental mammalian models provide evidence that even mild hyperthermia up to 2°C above normal significantly increases ischemic neuronal injury.3Keywords
This publication has 1 reference indexed in Scilit:
- Occurrence of potentially detrimental temperature alterations in hospitalized patients at risk for brain injuryJournal of Neurosurgical Anesthesiology, 1999