Effect of Cortisone and of Aureomycin on Baby Pigs Fed a Vitamin B12-Deficient Diet

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Abstract
A vit. B12 deficiency was produced in baby pigs fed an alpha-protein "synthetic milk" diet. The addition of aureomycin to this diet, either before or after the deficiency state existed, did not give a beneficial response. Intramusc. injn. of 30 [mu]g. of vit. B12 for 3 successive days into 2 of the deficient pigs caused a very marked reticulo-cytosis, a 4-fold increase in food consumption, and a significantly improved growth rate. The injn. of 20 mg. of cortisone daily into vit. B12-deficient pigs enhanced the deficiency state rather than having any curative effect.