Relation between Basement Membrane Degradation and Serum Levels of Laminin P1 in Patients with Transitional Cell Carcinoma of the Bladder
- 1 January 1993
- journal article
- research article
- Published by S. Karger AG in Urologia Internationalis
- Vol. 50 (1) , 13-16
- https://doi.org/10.1159/000282440
Abstract
In 47 patients with transitional cell carcinoma (TCC) of the bladder, we investigated the relationship between tissue laminin distribution and serum laminin levels. The results were compared with those obtained from 6 patients with pathologically proven normal bladder mucosa as well as those obtained previously from 50 controls and 16 patients with benign bladder disorders. Interruption of the basement membrane (BM) laminin staining pattern was correlated with high serum laminin levels (r = 0.34; pKeywords
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