Adrenaline Synthesis: Control by the Pituitary Gland and Adrenal Glucocorticoids
- 10 December 1965
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 150 (3702) , 1464-1465
- https://doi.org/10.1126/science.150.3702.1464
Abstract
The activity of phenylethanolamine-N-methyl transferase, an enzyme that synthesizes adrenaline from noradrenaline in the adrenal medulla, is markedly depressed following hypophysectomy. Enzyme activity is restored to normal after administration of ACTH or the potent glucocorticoid, dexamethasone. Thus the biosynthesis of adrenaline in the adrenal medulla appears to be regulated by the pituitary-adrenocortical system.This publication has 7 references indexed in Scilit:
- Purification and Properties of Phenylethanolamine-N-methyl TransferasePublished by Elsevier ,2021
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- Improved Technique for the Fluorimetric Estimation of CatecholaminesActa Physiologica Scandinavica, 1961
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- The formation of adrenaline from noradrenalineBiochimica et Biophysica Acta, 1957
- ON THE MORPHOLOGY AND ADRENALINE-NORADRENALINE CONTENT OF CHROMAFFIN TISSUEJournal of Endocrinology, 1953
- SPECIES DIFFERENCES IN ADRENOCORTICAL SECRETIONJournal of Endocrinology, 1953