ATYPICAL PORTER-SILBER REACTION AFTER THE ADMINISTRATION OF SULFAMERAZINE
- 1 September 1955
- journal article
- letter
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 15 (9) , 1152-1154
- https://doi.org/10.1210/jcem-15-9-1152
Abstract
Butanol extracts of the urine of patients treated with sulfamerazine contain a compound, which develops an orange color with phenylhydrazine in H2SO4 (absorption maximum at 4850 A.). The absorption band of this colored product covers the absorption region of the typical Porter-Silber chromogens. After the administration of therapeutic doses of sulfamerazine the orange color is so intense, that it is not possible to apply the method of Reddy, Jenkins and Thorn for the determination of corticoids to these urines.Keywords
This publication has 2 references indexed in Scilit:
- A NOTE OF CAUTION ON THE LACK OF SPECIFICITY OF THE PORTER-SILBER REACTION FOR 17,21-DIHYDROXY-20-KETOSTEROIDSJournal of Clinical Endocrinology & Metabolism, 1954
- ESTIMATION OF 17-HYDROXYCORTICOIDS IN URINE1952